Vardenafil hydrochloride trihydrate（b）

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Vardenafil HCl Trihydrate is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.

Vardenafil, also known as BAY 38-9456, is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil (VAR) is synthetic, highly selective, and potent inhibitor of phosphodiesterase-5 which competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. It is clinically approved for treatment of erectile dysfunction in men, including diabetic and postprostatectomy patients.

BAY 38-9456;Vardenafil HCl; Levitra; Staxyn; Vivanza

Others

Other Targets

PDE1; PDE5

Cardiovascular Disease

——

330808-88-3

579.11

C23H32N6O4S·HCl·3H2O

98%

——

n12[nH]c(nc(=O)c1c(nc2CCC)C)c1c(ccc(c1)S(=O)(=O)N1CCN(CC1)CC)OCC.Cl.O.O.O

2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one dihydrochloride trihydrate

(-20℃)

With Ice Pack

≥ 2 years